Impact of duration of Infertility on the Physiological Viability of Sperms Preparing for Intrauterine Insemination among Yemeni Infertile Males

Sadeq Saad Abd El Moghny1, Ahmed Kaid Allow1, Belqees Ahmed2 and Bracamonte Maryam2 

1 Department of Physiology, Faculty of medicine and Health Sciences, Sana’a University, Yemen

2Department of Basic Medical Science, Faculty of Medicine, International Islamic University Malaysia,


Infertility is defined as inability to conceive after 1 year of un-protective intercourse1,2 Pregnancy represents the successful and timely conclusion of series of physiological events: ovulation of a mature oocyte, production of viable sperm, association of oocyte and sperm in the reproductive tract, making of a viable embryo, embryo carriage into the uterine cavity, and embryo implantation within the endometrial cavity. Any disruption in these essential steps will lead to infertility [3, 4]. Secondary infertility is defined as the inability to become pregnant, or to carry a pregnancy to term, following the birth of one or more biological children [3]. About 30% of the infertile cases

are solely attributed to the male partner, 30% to female partner, 25% of cases are caused by a combination of male and female factors and about 15% unexplained infertility [5, 6]. Most of the infertility treatments are dependent on the underlying cause of infertility [7]. Some infertile couples nevertheless need more complex medical intervention like ARTs which is referred to many methods designed to overcome barriers to natural fertilization [8]. Over all, the estimated number of infertile patients treated by ART is around 20%. The goal is to increase the success rate of ART both in term of achieving pregnancy and in making sure that the pregnancy result in a genetically healthy individual [9]. The duration of

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