Red Marrow Carboxyhemoglobin Concentration at Lethal Carbon Monoxide Poisoning for Incinerated Corpses

Ali Ali Al-Turki.1*, Tetyuev A.M.2, Danchenko E.O.3

1Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine and Health Sciences, Sana’a University

2Department of Forensic Medicine, Vitebsk State Medical University

3Forensic Chemistry Department, Vitebsk Region Administration of State Committee of Forensic Expertise of the Republic of Belarus

Introduction:

Carboxyhemoglobin (COHb) is astable complex of carbon monoxide (CO and hemoglobin (Hb) that forms in red blood cells upon contact with CO. Exposure to small concentrations of CO hinder the ability of Hb to deliver oxygen to the body because of carboxyhemoglobin forms more readily than does oxyhemoglobin (HbO2). CO is produced in normal metabolism and is also a common chemical. Tobacco smoking (through carbon monoxide inhalation) raises the blood levels of COHb by a factor of several times from its normal concentrations1.CO poisoning in fire accidents or

catastrophes in the Republic of Belarus considers about 15–20% of all poisonings, and about 5% of all violent deaths. Medico-legal diagnosis of CO poisoning is mainly based on the results of СОНb quantification in blood samples. However, it may be impossible to sample liquid blood from incinerated, exsanguinated or dismembered the corpse. Babakhanyan and Busova examined COHb in dried blood spots using quantitative spectrophotometric analysis2 and found that COHb in dry blood spots was 28%–66 % while COHb in the liquid blood was 46%–87%. Ageeva et al.3 COHb concentration in cadaveric internal organs and muscles. According to their findings,

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