The Histopathological Patterns of Prostatic Diseases and Prostatic Cancer in Yemeni Patients

 1Abdullah Saleh Al-Samawi, M.Phill, MCPS ,1Saleh Mansoor Aulaqi, FRCPC

1From Department of Pathology, Faculty of Medicine and Health Sciences Sana'a University. Sana'a Yemen

Introduction:

Prostatic diseases are responsible for significant morbidity and mortality among adult males worldwide1. Most frequently encountered diseases affecting prostate are prostatitis, benign prostatic hyperplasia (BPH) and prostatic cancer1. Prostate cancer is the most common malignant tumor in men all over the world and is also the second important cause of cancer related deaths in men after lung cancer2. The average age at the time of diagnosis is about 67 year. Prostate cancer can be a serious disease, but most men diagnosed with prostate cancer do not die from it3. Adenocarcinoma is the most common histological variant of prostatic cancer1. Once the diagnosis of cancer is made, tumor grading, especially the

Gleason score, strongly influences decisions regarding options for therapy4. However, the most important risk factors for developing prostate carcinoma are family history, increasing age, lack of exercise and high calcium intake5. BPH or nodular hyperplasia is the non-malignant adenomatous growth characterized by hyperplasia of stroma and epithelial parenchyma, resulting in the difficulty of urination and in extreme cases, completely impossible6,7. Statistical observations suggest that a diet low in fat and red meat and high in protein and vegetables, could protect against BPH8. Inflammation of prostatic gland is characterized by urinary frequency, dysuria, body aches and sometimes fever. It is estimated that number of males in the United States who will experience prostatitis

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An Academic Biannual Refereed Journal, Published by Sana'a University

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