Developmental changes in the morphology of human thyroid gland at different gestational age

Saleem Alriashi1, Saleh Almarashi2, Chhaya Sawant3 , M.Layeeque4

1 Department of Anatomy, Faculty of Medicine and Health Sciences, Sana'a University, Sana'a, Yemen
2Department of Anatomy, Faculty of Medicine and Health Sciences, Sana'a University, Sana'a, Yemen
3 Department of medicine, Kuwait university hospital, Sana'a, Yemen
4 Department of Anatomy, govt. medical college , DR.B.A.M. University, A ` bad , India


Since 1600 BC the Chinese were using burnt sponge and seaweed for the treatment of goitres.
In human beings the thyroid gland is one of the largest and the earliest endocrine organ to differentiate and has an important hormonal role in embryonic development.
The important function of thyroid hormones is
to maintain the optimal level of metabolism for the normal functioning of almost all the body cells.
Thyroid hormones stimulate the oxygen consumption of most of the cells in the body, help to regulate lipid and carbohydrate metabolism and are necessary for normal growth and maturation.
The importance of the thyroid gland lies in the fact that it promotes growth and development of the brain during fetal life and the first few years of postnatal life. Iodine deficiency is the single most common cause of preventable

mental retardation and brain damage in the world. It causes enlargement of thyroid (goiter) and decreases production of hormones vital to growth and development.
The Thyroid gland is not essential for life, although its absence causes mental and physical slowing, poor resistance to cold and mental retardation and dwarfism in children.
Aims and Objectives
The aim of the present study is:
To correlate the weight of fetal thyroid with body weight crown-rump length, and estimated gestational age of fetus
Materials and Methods
Collection of Materials
In the present study 50 still born, normal fetuses (30 Male, 20 Female) were obtained with the permission of prof. and head of department of obstetrics and Gynecology,

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An Academic Biannual Refereed Journal, Published by Sana'a University

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